Fertility: Studies have not been performed to evaluate the effects of topical ocular administration of atropine on fertility.
Use in Pregnancy: There are no or limited amount of data from the use of ATROPINE sulfate Sterile Ophthalmic Solution in pregnant women. Animal studies are insufficient with respect to reproductive toxicity. There are documented systemic effects stemming from ophthalmic atropine.
Use in Lactation: It is unknown whether Atropine is excreted in human milk. However, atropine and antimuscarinic agents have been shown to adversely affect lactation in preclinical and in clinical studies.